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Updated: 9 min 18 sec ago

Orexo nabs regulatory win for fast-dissolving opioid dependence therapy

November 20, 2017 - 9:09am
Orexo (STO:ORX) said today that the European Medicines Agency granted marketing authorization for its Zubsolv rapidly-disintegrating treatment for opioid dependence. The buprenorphine and naloxone sublingual tablet is the first to be approved in Europe with six different strengths, according to the Sweden-based company. Get the full story at our sister site, Drug Delivery Business News. The post Orexo nabs regulatory win for fast-dissolving opioid dependence therapy appeared first on MassDevice. (Source: Mass Device)

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Long- and Short-Acting Opioid Addiction Meds Equally Effective Long- and Short-Acting Opioid Addiction Meds Equally Effective

November 16, 2017 - 10:12am
Extended-release naltrexone and buprenorphine/naloxone are similarly efficacious in preventing relapse for patients with opioid use disorder, although naltrexone was more difficult to initiate.Medscape Medical News (Source: Medscape Medical News Headlines)

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Opioid Addiction Treatments Face Off in US Trial

November 15, 2017 - 10:47am
CHICAGO (AP) — The first U.S. study to compare two treatments for opioid addiction finds a monthly shot works as well as a daily drug to prevent relapse. The shot requires days of detox first and that proved to be a stumbling block for many. For those who made it past that hurdle, the shot Vivitrol worked about the same as an older treatment, Suboxone. Both drugs had high relapse rates and there were overdoses, including fatal ones, in the experiment in 570 adults. The study , published Tuesday in the journal Lancet, is the first to compare the two drugs in the United States, where an opioid addiction epidemic has doctors and policymakers deeply divided over treatment strategies. Many addiction treatment programs don't offer either medication, or only one of them. "Let's not keep ar...

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Study: Head-to-head comparison of opioid use disorder therapies finds similarities

November 15, 2017 - 8:14am
A study published today in The Lancet found that two different therapies used to treat opioid use disorder – an extended-release naltrexone injection and a combination of buprenorphine and naloxone – have similar outcomes once patients get past the hurdle of starting treatment. This is the first study to compare the combination therapy and naltrexone head-to-head in the U.S. The study enrolled 570 opioid-dependent adults, 82% of which were using heroin and 16% of which were abusing pain medications. Get the full story at our sister site, Drug Delivery Business News. The post Study: Head-to-head comparison of opioid use disorder therapies finds similarities appeared first on MassDevice. (Source: Mass Device)

Opioid treatment drugs have similar outcomes once patients initiate treatment

November 14, 2017 - 12:19pm
NIDA study compares buprenorphine/naloxone combination to extended release naltrexone. (Source: National Institutes of Health (NIH) News Releases)

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Pediatricians ’ Counseling Hopes To End Teen Opioid Addiction Before It Starts

October 24, 2017 - 4:18pm
WAREHAM (CBS) – One out of every four teenagers admits to misusing or abusing, a prescription drug. It’s a dangerous road that can lead to addiction. To prevent and treat drug-use in kids there is now a first-of-its-kind program tackling the issue head-on right at the pediatrician’s office. At Wareham Pediatrics, the Cat in the Hat welcomes young patients and route markers provide a guide to the exam rooms. (WBZ-TV) But the practice itself could be creating a road map to prevent and treat addiction in kids. (WBZ-TV) “It was a really helpless feeling to sometimes see kids and families struggling with drug, alcohol, or even worse opiate use and not have the tools,” Dr. Jason Reynolds told WBZ-TV. Wareham Pediatrics now has those tools. It is believed to be the o...

Opioid Blocker as Good as Suboxone in First Head-to-Head Trial (CME/CE)

October 20, 2017 - 9:35am
(MedPage Today) -- Monthly naltrexone (Vivitrol) non-inferior to buprenorphine/naloxone (Source: MedPage Today Pain Management)

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Extended-Release Naltrexone Seems as Effective as Standard Treatment for Opioid Dependence (FREE)

October 18, 2017 - 7:00pm
By Amy Orciari Herman Edited by Susan Sadoughi, MD Injectable extended-release naltrexone (Vivitrol) appears to be as safe and effective as daily oral buprenorphine-naloxone for treating opioid dependence, according to a Norway-based, noninferiority trial … (Source: Physician's First Watch current issue)

CHMP Backs Two Drugs for Opioid Abuse CHMP Backs Two Drugs for Opioid Abuse

September 15, 2017 - 10:44am
The EMA committee recommends naloxone nasal spray (Nyxoid) for treatment of opioid overdose and buprenorphine plus naloxone sublingual tablets (Zubsolv) for treatment of opioid dependence.International Approvals (Source: Medscape Medical News Headlines)

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Addressing stigma in medication treatment of adolescents with opioid use disorder - Bagley SM, Hadland SE, Carney BL, Saitz R.

August 7, 2017 - 10:20am
: In September 2016, the American Academic of Pediatrics released a policy statement that adolescents with opioid use disorder should be offered pharmacotherapy with buprenorphine/naloxone, methadone, or naltrexone. In our clinical practice, however, we ha... (Source: SafetyLit)

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