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Karyotyping
Description:
Morphological evaluation of chromosomes is done by creating a picture, called a karyotype, of the chromosomes in a single cell. A karyotype can be created from a variety of samples, including blood, bone marrow, amniotic fluid, or placental tissue. Each sample is cultured in the laboratory; when ready, the cells are harvested. The chromosomes they contain are then stained, viewed under a microscope, and arranged into 23 pairs. Each of the 23 pairs of chromosomes has a very characteristic appearance and can be differentiated from one another by length and the stain-induced black and white banding pattern.
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