Buprenorphine News Feed

Exploration of the telescoping effect among not-in-treatment, intensive heroin-using research volunteers - Stoltman JJ, Woodcock EA, Lister JJ, Greenwald MK, Lundahl LH.

MedWorm Addiction Feeds - January 31, 2015 - 9:32pm
BACKGROUND: Addiction research literature suggests some demographic groups exhibit a later age of substance use initiation, more rapid escalation to dependence, and worse substance use-related outcomes. This 'telescoping' effect has been observed more ofte... (Source: SafetyLit: All (Unduplicated))

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Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function

MedWorm Addiction Feeds - January 31, 2015 - 6:00pm
This article is protected by copyright. All rights reserved. (Source: Journal of Neurochemistry)

Multigenerational prenatal stress increases the coherence of brain signaling among cortico–striatal–limbic circuits in adult rats

MedWorm Addiction Feeds - January 31, 2015 - 6:00pm
Publication date: 19 March 2015 Source:Neuroscience, Volume 289 Author(s): I. Skelin , M.A. Needham , L.M. Molina , G.A.S. Metz , A.J. Gruber Prenatal stress (PNS) is a significant risk factor for the development of psychopathology in adulthood such as anxiety, depression, schizophrenia and addiction. Animal models of PNS resemble many of the effects of PNS on humans and provide a means to study the accumulated effects of PNS over several generations on brain function. Here, we examined how mild PNS delivered during the third week in utero over four consecutive generations affects behavioral flexibility and functional signaling among cortical and limbic structures. These multi-generational prenatally stressed (MGPNS) rats were not impaired on an odor-cued reversal learning task as compar...

Binge-Watching Netflix Is Making You Feel Lonely And Depressed

MedWorm Addiction Feeds - January 31, 2015 - 9:51am
Settling in on the couch with a bottle of wine and an entire season of Friends may seem like a perfectly enjoyable way to spend the weekend, but regular binge-watching sessions may be a sign of mental health problems. A new study from the University of Texas at Austin found that the more lonely and depressed people are, the more likely they are to binge-watch television. The researchers conducted a survey on over 300 millennials, asking how often and how much they watched TV, how often they felt lonely, and examining various measures of depression and self-regulation. Those who lacked self-regulatory skills reported being unable to stop clicking "next" even though they knew there were other things they needed to do, indicating a lack of self-control. The data also showed that feelings ...

Co-occurrence of alcohol use disorder and behavioral addictions: relevance of impulsivity and craving - Di Nicola M, Tedeschi D, De Risio L, Pettorruso M, Martinotti G, Ruggeri F, Swierkosz-Lenart K, Guglielmo R, Callea A, Ruggeri G, Pozzi G, Di...

MedWorm Addiction Feeds - January 30, 2015 - 11:57pm
PURPOSE: The aims of the study were to evaluate the occurrence of behavioral addictions (BAs) in alcohol use disorder (AUD) subjects and to investigate the role of impulsivity, personality dimensions and craving. METHODS: 95 AUD outpatients (DSM-5)... (Source: SafetyLit: All (Unduplicated))

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Why Positive Thinking Doesn't Always Work

MedWorm Addiction Feeds - January 30, 2015 - 10:06pm
I often hear "think positive and everything will work out." We may tell ourselves to think positive and say lots of positive affirmations and yes, sometimes this positive attitude does in fact create an energy that will bring us to the next right place. However, if we are not in tune with what our subconscious beliefs are, we will find ourselves spinning in circles and continue to create the same unwanted results over and over again. Attempting to just think positive can keep us feeling like we are stuck in a spin cycle because under these thoughts and happy demeanor, something is lurking around in the dark and until we are willing to shine a bright light on it, it will continue to direct our lives. This "something" is called our Ego. It is the voice that hangs out in our head and sends u...

Novel Approaches to Individual Alcohol Interventions for Heavy Drinking College Students and Young Adults

MedWorm Addiction Feeds - January 30, 2015 - 6:00pm
Abstract Efficacious alcohol interventions for college students and young adults have been developed but produce small effects of limited duration. This paper provides a review and critique of novel (e.g., a significant deviation from a traditional, brief, and motivational intervention) interventions published between 2009 and 2014 to reduce alcohol use in this population and covers intervention format/components and efficacy on alcohol outcomes. We reviewed 12 randomized controlled trials of novel, individual-level alcohol interventions that reported alcohol outcomes. Four domains of novel interventions are discussed: content (e.g., pharmacotherapy and automatic action tendency retraining), setting (e.g., health centers and ED), modality (e.g., mobile technology), and treatment i...

Investigating the microstructural and neurochemical environment within the basal ganglia of current methamphetamine abusers

MedWorm Addiction Feeds - January 30, 2015 - 6:00pm
Methamphetamine is a highly addictive psychostimulant and the medical, social, and economic consequences associated with its use have become a major international problem. Addiction is one of the most pervasive, costly, and challenging health problems facing society, and the use and manufacture of amphetamines remain high. The number of amphetamine users worldwide likely exceeds the number of opiate and cocaine users combined (United Nations Office on Drugs and Crime, 2010). Current evidence suggests that long-term exposure to psychostimulants such as methamphetamine is associated with structural, metabolic, and neurochemical changes in both gray and white matter (Bae et al., 2006; London et al., 2004; Thompson et al., 2004). (Source: Drug and Alcohol Dependence)

Harm Reduction in U.S. Tobacco Control: Constructions in Textual News Media

MedWorm Addiction Feeds - January 30, 2015 - 6:00pm
In the United States, tobacco smoking remains the leading preventable cause of disease and death (U.S. Department of Health and Human Services, 2014). Adult smoking rates peaked at roughly 42% in 1964 and have fallen steadily since (Bolden, 2010; Warner, 2006); currently about 20% of U.S. adults smoke, with the highest rates among non-whites, the poorer and less educated, and those with mental health and substance abuse disorders (Centers for Disease Control, 2014). U.S. tobacco control and public health policies addressing smoking have long emphasized abstinence - primary prevention and cessation based interventions for current smokers; yet cessation rates are low and nicotine replacement therapies (NRT) (patches, gum, medication) are not appealing to all smokers, limiting options for tho...

AAP Discourages the Legalization of Marijuana

MedWorm Addiction Feeds - January 30, 2015 - 3:35pm
There has been an on going discussion about the legalization of marijuana for medical or recreational use. Pediatric Health Associates and the American Academy of Pediatrics [AAP] strongly discourages the use of marijuana in our patient population.We discourage the use of marijuana in teens due to the well documented adverse affects and the serious health concerns. These effects include impaired short term memory, decreased concentration, decreased attention span, lower IQ and decreased problem solving. These factors would clearly interfere with a teens ability to learn and thrive in a school setting. Further, we know that a significant percentage of teen users suffer depression and increased anxiety after using marijuana.Research tells us that early...

SAMHSA moves toward allowing Block Grant funds for co‐pays

MedWorm Addiction Feeds - January 30, 2015 - 1:56pm
(Source: Alcoholism and Drug Abuse Weekly)

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UCLA cardiologists offer heart-healthy tips

MedWorm Addiction Feeds - January 30, 2015 - 11:00am
UCLA Exercise is a key way to keep your heart healthy. With the arrival of American Heart Month in February, it’s that time of the year to remind ourselves to take good care of our hearts. To that end, cardiologists from the UCLA Barbra Streisand Women’s Heart Health Program, point out lifestyle factors that can help lower heart disease risk in both men and women. “In addition to following a healthy diet and staying active, there are other things that we can do every day to help protect our hearts such as staying socially connected and getting enough sleep,” said Dr. Karol Watson, director of the heart program. Watson, who is also a professor of medicine, division of cardiology at the David Geffen School of Medicine at UCLA, says that as a country we’re making good strides in th...

Mental Health: The $293 Billion Elephant in the Waiting Room

MedWorm Addiction Feeds - January 30, 2015 - 9:30am
According to data from the Substance Abuse and Mental Health Services Administration, more than 41 million (18 percent) American adults had some form of mental illness and nearly 20 million (8 percent) had an addiction in 2011. Costs for treating patients with chronic medical conditions accompanied by mental illnesses and addictions can be two to three times higher than those without these disorders, totaling an estimated $293 billion in 2012 across commercially-insured, Medicaid and Medicare beneficiaries in the United States. (Source: Disabled World)

Morning Break: Arrgh ... A Pirate's Medicine Chest; Hardwired for Addiction?

MedWorm Addiction Feeds - January 30, 2015 - 7:45am
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff. (Source: MedPage Today Psychiatry)

Bunavail: another buprenorphine/naloxone formulation for opioid dependence.

Pub Med: Keyword Buprenorphine - January 30, 2015 - 6:30am
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Bunavail: another buprenorphine/naloxone formulation for opioid dependence.

Med Lett Drugs Ther. 2015 Feb 2;57(1461):19-20

Authors:

PMID: 25629812 [PubMed - in process]

Past-year gambling behaviour among patients receiving opioid substitution treatment.

Pub Med: Keyword Buprenorphine - January 30, 2015 - 6:30am
Related Articles

Past-year gambling behaviour among patients receiving opioid substitution treatment.

Subst Abuse Treat Prev Policy. 2015 Jan 27;10(1):4

Authors: Castrén S, Salonen AH, Alho H, Lahti T, Simojoki K

Abstract
BACKGROUND: Substance abuse and gambling problems are associated, however, studies on gambling problems among opioid substitution treatment (OST) patients are scarce. The aims of this study are to explore the association of gender, age, treatment medication and treatment program with gambling behaviour, including gambling participation and gambling problems, among OST patients.
FINDINGS: All OST patients (n = 244) in three Finnish outpatient clinics were recruited in March - April 2014. The response rate was 64.3%. OST programs included two choices of orientation (rehabilitative/harm reduction) and two choices for treatment medication (methadone/buprenorphine-naloxone). Of 144 respondents, 70.1% had gambled during the past year and 12.5% were identified as potential past-year problem gamblers. Gambling was statistically significant more commonly among males (79.8%) compared with females (53.7%). Similarly patients in the rehabilitative program gambled (75.9%) more than those in the harm reduction program (50.0%). Gender, age, treatment medication or treatment program was not associated with past-year gambling problems.
CONCLUSIONS: Gambling participation of the OST patients seemed to be somewhat similar compared with the Finnish general population, but gambling problems were more common among OST patients. Gender and age may not be very strong indicators of risk while screening problem gamblers among OST patients. Institution of a problem gambling screening program is recommended, and additional intervention for gambling problems should be implemented for that need as a part of OST.

PMID: 25626451 [PubMed - as supplied by publisher]

Tramadol for premature ejaculation: a systematic review and meta-analysis

MedWorm Addiction Feeds - January 29, 2015 - 6:00pm
Conclusions: Tramadol appears effective in the treatment of PE. However, these findings should be interpreted with caution given the observed levels of between-trial heterogeneity and the reporting quality of the available evidence. The variability across placebo-controlled trials in terms of the tramadol dose evaluated and the treatment duration does not permit any assessment of a safe and effective minimum daily dose. The long-term effects and side effects, including addiction potential, for men with PE have not been evaluated in the current evidence base.Trial registration: The review is registered on PROSPERO 2013:CRD42013005289. (Source: BioMed Central)

ADHD and autistic traits, family function, parenting style, and social adjustment for Internet addiction among children and adolescents in Taiwan: A longitudinal study

MedWorm Addiction Feeds - January 29, 2015 - 6:00pm
Publication date: April 2015 Source:Research in Developmental Disabilities, Volume 39 Author(s): Yi-Lung Chen , Sue-Huei Chen , Susan Shur-Fen Gau This longitudinal study investigated the prevalence, predictors, and related factors for Internet addiction among elementary and junior high school students in Taiwan. A convenient sample of grades 3, 5, and 8 students (n =1153) was recruited from six elementary and one junior high schools. They were assessed during the beginning and the end of the spring semester of 2013. Internet addiction was examined by the Chen Internet Addiction Scale (CIAS). Other factors were screened using the Chinese version of the Autism Spectrum Quotient (AQ) for autistic trait, the Parental Bonding Instrument (PBI) for parenting, the Family APGAR for family suppor...

Efficacy of a smoking prevention programme in Catalan secondary schools: a cluster‐randomized controlled trial in Spain

MedWorm Addiction Feeds - January 29, 2015 - 6:00pm
ConclusionsA school‐based educational intervention for secondary school students in Catalonia, Spain was not found to lead to a statistically significant reduction of smoking prevalence and incidence. (Source: Addiction)

Trends in Abuse and Misuse of Prescription Opioids Among Older Adults

MedWorm Addiction Feeds - January 29, 2015 - 6:00pm
We examined recent trends in the abuse and misuse and associated fatal outcomes among older adults (60+ years) and compared these to trends among younger adults (20-59 years). METHODS: Trend analysis using linear regression models was used to analyze 184,136 cases and 1,149 deaths associated with abuse and misuse of the prescription opioids oxycodone, fentanyl, hydrocodone, morphine, oxymorphone, hydromorphone, methadone, buprenorphine, tramadol, and tapentadol that were reported to participating U.S. (Source: Drug and Alcohol Dependence)

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